2026年开年的BD热潮，为这一问题提供了清晰的答案。以石药集团为例，12亿美元首付款（约合人民币87亿元）将直接计入当期利润，显著改善财务报表；后续的35亿美元研发里程碑和138亿美元销售里程碑，为未来多年的业绩提供了可见的增量。信达生物的3.5亿美元首付款、荣昌生物的6.5亿美元首付款，都将直接增厚公司的净利润。
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For implementers, the locking model adds a fair amount of non-trivial internal bookkeeping. Every operation must check lock state, readers must be tracked, and the interplay between locks, cancellation, and error states creates a matrix of edge cases that must all be handled correctly.